Eight-time winners Lyon came from behind to defeat Benfica and put themselves in a strong position to progress from the quarter-finals of the Women’s Champions League.
The hosts took the lead through Portugal midfielder Andreia Faria’s composed finish in Lisbon.
Delphine Cascarino equalised before Germany midfielder Sara Dabritz headed the winner in the 79th minute.
The second leg takes place in France on 27 March (17:45 GMT).
Lyon, who last won the competition in 2022, will be favourites to finish the job next week.
Benfica had started strongly with Andrea Falcon having an attempt tipped on to the bar before Faria’s goal.
The winners of the tie will face Swedish side Hacken or Paris St-Germain over two legs in the semi-finals.
Line-ups
Benfica Women
Formation 3-5-2
- 1Powell
- 80dos Santos AraújoSubstituted forda Silva Seiçaat 63′minutes
- 15da Silva Costa
- 16UcheibeBooked at 66mins
- 13by Sousa AlvesBooked at 90mins
- 6Martins FariaSubstituted forDominguez Encinasat 69′minutes
- 10Ramos Ribeiro Nazareth SousaSubstituted forSilva Amadoat 69′minutes
- 23Gasper
- 28FalconSubstituted forNortonat 69′minutes
- 2Alidou
- 9Silva SobrinhoSubstituted forDavidsonat 16′minutes
Substitutes
- 3da Silva Seiça
- 4Garcia Rebelo
- 5Almendariz
- 8da Silva Cintra
- 17Norton
- 19Silva Amado
- 20Nogueira Martins
- 21Dominguez Encinas
- 25Davidson
- 66Costa Fields
- 71da Silva
- 99by Sá Pessoa Brás Nogueira
Lyon Women
Formation 4-2-3-1
- 1Ender
- 12Carpenter
- 21Gilles
- 29Mbock Bathy
- 4YouthBooked at 32mins
- 26Horan
- 8Däbritz
- 20CascarinoBooked at 90mins
- 7MajriSubstituted forDumornayat 55′minutes
- 11DianaSubstituted forShovelat 77′minutes
- 9Laugh SummerSubstituted forThe logat 55′minutes
Substitutes
- 3Renard
- 5Morroni
- 6Dumornay
- 10Marozsan
- 13The log
- 16Belhadj
- 18Sombath
- 19Sylla
- 27Shovel
- 30Benkarth
- 31Joseph
- 32Mendy
Live Text
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Match ends, Benfica Women 1, Lyon Féminines 2.
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Second Half ends, Benfica Women 1, Lyon Féminines 2.
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Attempt blocked. Lindsey Horan (Lyon Féminines) right footed shot from outside the box is blocked.
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Corner, Lyon Féminines. Conceded by Ana Seiça.
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Delphine Cascarino (Lyon Féminines) is shown the yellow card.
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Lúcia Alves (Benfica Women) is shown the yellow card for a bad foul.
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Delphine Cascarino (Lyon Féminines) wins a free kick in the defensive half.
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Foul by Lúcia Alves (Benfica Women).
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Attempt saved. Lindsey Horan (Lyon Féminines) left footed shot from the centre of the box is saved in the centre of the goal.
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Offside, Lyon Féminines. Melchie Dumornay is caught offside.
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Sara Däbritz (Lyon Féminines) wins a free kick on the left wing.
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Foul by Anna Gasper (Benfica Women).
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Delay over. They are ready to continue.
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Delay in match because of an injury Vicki Bècho (Lyon Féminines).
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Goal! Benfica Women 1, Lyon Féminines 2. Sara Däbritz (Lyon Féminines) header from very close range to the bottom left corner. Assisted by Lindsey Horan with a cross.
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Offside, Lyon Féminines. Lindsey Horan is caught offside.
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Substitution, Lyon Féminines. Vicki Bècho replaces Kadidiatou Diani.
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Lindsey Horan (Lyon Féminines) wins a free kick on the left wing.
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Foul by Ana Seiça (Benfica Women).
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Corner, Lyon Féminines. Conceded by Christy Ucheibe.