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AMD preps rack-scale Instinct MI450X IF128 with 128 GPUs to challenge Nvidia’s VR200 NVL144 in 2026

AMD preps rack-scale Instinct MI450X IF128 with 128 GPUs to challenge Nvidia’s VR200 NVL144 in 2026


AMD preps rack-scale Instinct MI450X IF128 with 128 GPUs to challenge Nvidia’s VR200 NVL144 in 2026

AMD plans to launch its first two rack-scale Instinct accelerators in 2026 to compete with Nvidia’s VR300 NVL144, reports SemiAnalysis. They are named AMD’s Instinct MI450X IF64 and Instinct MI450X IF128, and both are designed for AI deployment. If they prove to be a success, it could change the landscape of AI hardware over time.

While AMD’s Instinct MI300-series AI and HPC GPUs are very powerful on paper, they cannot compete against Nvidia’s GB200 NVL72 rack-scale solution in terms of performance scalability, as their maximum scale-up world size is eight processors.

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